Nutrition, Metabolism & Cardiovascular Diseases
Volume 17, Issue 9 , Pages 666-675, November 2007

Orange flavonoid hesperetin modulates cardiac hERG potassium channel via binding to amino acid F656

  • Eberhard P. Scholz

      Affiliations

    • Department of Cardiology, Medical University Hospital Heidelberg, Im Neuenheimer Feld 410, D-69120 Heidelberg, Germany
    • Corresponding Author InformationCorresponding author. Tel.: +49 6221 563 8881; fax: +49 6221 4876 8902.
    • These authors contributed equally to this work.
    • ,
  • Edgar Zitron

      Affiliations

    • Department of Cardiology, Medical University Hospital Heidelberg, Im Neuenheimer Feld 410, D-69120 Heidelberg, Germany
    • These authors contributed equally to this work.
    • ,
  • Claudia Kiesecker

      Affiliations

    • Department of Cardiology, Medical University Hospital Heidelberg, Im Neuenheimer Feld 410, D-69120 Heidelberg, Germany
    • ,
  • Dierk Thomas

      Affiliations

    • Department of Cardiology, Medical University Hospital Heidelberg, Im Neuenheimer Feld 410, D-69120 Heidelberg, Germany
    • ,
  • Sven Kathöfer

      Affiliations

    • Department of Cardiology, Medical University Hospital Heidelberg, Im Neuenheimer Feld 410, D-69120 Heidelberg, Germany
    • ,
  • Jörg Kreuzer

      Affiliations

    • St. Vincenz Hospital, Limburg, Germany
    • ,
  • Alexander Bauer

      Affiliations

    • Department of Cardiology, Medical University Hospital Heidelberg, Im Neuenheimer Feld 410, D-69120 Heidelberg, Germany
    • ,
  • Hugo A. Katus

      Affiliations

    • Department of Cardiology, Medical University Hospital Heidelberg, Im Neuenheimer Feld 410, D-69120 Heidelberg, Germany
    • ,
  • Andrew Remppis

      Affiliations

    • Department of Cardiology, Medical University Hospital Heidelberg, Im Neuenheimer Feld 410, D-69120 Heidelberg, Germany
    • ,
  • Christoph A. Karle

      Affiliations

    • Department of Cardiology, Medical University Hospital Heidelberg, Im Neuenheimer Feld 410, D-69120 Heidelberg, Germany
    • ,
  • Johannes Greten

      Affiliations

    • German Society of Traditional Chinese Medicine, Heidelberg, Germany

Received 29 March 2006; received in revised form 13 June 2006; accepted 17 June 2006. published online 22 August 2006.

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PII: S0939-4753(06)00140-2

doi:10.1016/j.numecd.2006.06.002

Nutrition, Metabolism & Cardiovascular Diseases
Volume 17, Issue 9 , Pages 666-675, November 2007

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