Nutrition, Metabolism & Cardiovascular Diseases
Volume 20, Issue 5 , Pages 350-358 , June 2010

Cardiovascular disease prevalence and its relation to risk factors in Alaska Eskimos

  • Barbara V. Howard

      Affiliations

    • MedStar Research Institute, Hyattsville, MD, USA
    • Corresponding Author InformationCorresponding author at: MedStar Research Institute, Georgetown University, 6495 New Hampshire Avenue, Suite 201, Hyattsville, MD 20783, USA. Tel.: +1 301 560 7302; fax: +1 301 560 7307.
  • ,
  • Anthony Comuzzie

      Affiliations

    • Southwest Foundation for Biomedical Research, San Antonio, TX, USA
  • ,
  • Richard B. Devereux

      Affiliations

    • Weill Medical College of Cornell University, New York, NY, USA
  • ,
  • Sven O.E. Ebbesson

      Affiliations

    • Norton Sound Health Corporation, Nome, AK, USA
  • ,
  • Richard R. Fabsitz

      Affiliations

    • National Heart, Lung, and Blood Institute, Bethesda, MD, USA
  • ,
  • Wm. James Howard

      Affiliations

    • Washington Hospital Center, Washington, DC, USA
  • ,
  • Sandra Laston

      Affiliations

    • Southwest Foundation for Biomedical Research, San Antonio, TX, USA
  • ,
  • Jean W. MacCluer

      Affiliations

    • Southwest Foundation for Biomedical Research, San Antonio, TX, USA
  • ,
  • Angela Silverman

      Affiliations

    • MedStar Research Institute, Hyattsville, MD, USA
  • ,
  • Jason G. Umans

      Affiliations

    • MedStar Research Institute, Hyattsville, MD, USA
  • ,
  • Hong Wang

      Affiliations

    • MedStar Research Institute, Hyattsville, MD, USA
  • ,
  • Neil J. Weissman

      Affiliations

    • MedStar Research Institute, Hyattsville, MD, USA
  • ,
  • Charlotte R. Wenger

      Affiliations

    • Southwest Foundation for Biomedical Research, San Antonio, TX, USA

Received 24 December 2008 ,Revised 17 April 2009 ,Accepted 20 April 2009.

References 

  1. Dyerberg J, Bang HO, Hjorne N. Fatty acid composition of the plasma lipids in Greenland Eskimos. Am J Clin Nutr. 1975 Sep;28(9):958–966
  2. <http://www.hss.state.ak.us/dph/bvs/>.
  3. National Center for Health Statistics , Gittelsohn A, Royston P. In: Annotated bibliography of cause-of-death validation studies, 1958–1980. Vital and health statistics, series 2, no. 89. Washington, DC: Govt Printing Office; September 1982;[DHHS Pub. No. (PHS) 82-1363]
  4. Lanier AP, Ehrsam G, Sardidge J. Alaska Native mortality 1989–1998. Office of Alaska Native Health Research, Division of Community Health Services, Alaska Native Tribal Health Consortium; 2002;
  5. Bjerregaard P, Young TK, Hegele RA. Low incidence of cardiovascular disease among the Inuit – what is the evidence?. Atherosclerosis. 2003;166:351–357
  6. Young TK, Moffatt ME, O'Neil JD. Cardiovascular diseases in a Canadian Arctic population. Am J Public Health. 1993;83:881–887
  7. Hegele RA, Young TK, Connelly PW. Are Canadian Inuit at increased genetic risk for coronary heart disease?. J Mol Med. 1997;75:364–370
  8. Boudreau DA, Scheer WD, Malcom GT, Mulvad G, Pedersen HS, Jul E. Apolipoprotein E and atherosclerosis in Greenland Inuit. Atherosclerosis. 1999;145:207–219
  9. Pederson HS, Mulvad G, Newman WP, Boudreau DA. Atherosclerosis in coronary arteries and aorta among Greenlanders: an autopsy study. Atherosclerosis. 2003;170:93–103
  10. Hegele RA. Genetic prediction of atherosclerosis: lessons from studies in native Canadian populations. Clin Chim Acta. 1999;286:47–61
  11. Bjerregaard P, Young TK, Dewailly E, Ebbesson SO. Indigenous health in the Arctic: an overview of the circumpolar Inuit population. Scand J Public Health. 2004;32:390–395
  12. Howard BV, Devereux RB, Cole SA, Davidson M, Dyke B, Ebbesson SO, et al. A genetic and epidemiologic study of cardiovascular disease in Alaska natives (GOCADAN): design and methods. Int J Circumpolar Health. 2005 Jun;64(3):206–221
  13. Ebbesson SO, Laston S, Wenger CR, Dyke B, Romenesko T, Swenson M, et al. Recruitment and community interactions in the GOCADAN study. Int J Circumpolar Health. 2006;65:55–64
  14. National Institutes of Health . Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults – the evidence report. Obes Res. 1998;6(Suppl. 2):51S–209S
  15. Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure . The sixth report of the joint national committee on prevention, detection, evaluation, and Treatment of High Blood Pressure. Arch Intern Med. 1997;157:2413–2446
  16. Okin PM, Devereux RB, Howard B, Fabsitz RR, Lee ET, Welty TJ. Assessment of QT interval and QT dispersion for prediction of all-cause and cardiovascular mortality in American Indians: the Strong Heart Study. Circulation. 2000;101:61–66
  17. Nobmann ED, Ponce R, Mattil C, Devereux R, Dyke B, Ebbesson SO, et al. Dietary intakes vary with age among Eskimo adults of Northwest Alaska in the GOCADAN study, 2000–2003. J Nutr. 2005 Apr;135(4):856–862
  18. Ainsworth BE, Haskell WL, Whitt MC, Irwin ML, Swartz AM, Strath SJ, et al. Compendium of physical activities: an update of activity codes and MET intensities. Med Sci Sports Exerc. 2000 Sep;32(9 Suppl.):S498–S504
  19. Expert Committee on the Diagnosis and Classification of Diabetes Mellitus . Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care. 1997;20:1183–1197
  20. Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem. 1972;18:499–502
  21. Zhu J, Katz RJ, Quyyumi AA, Canos DA, Rott D, Csako G, et al. Association of serum antibodies to heat-shock protein 65 with coronary calcification levels: suggestion of pathogen-triggered autoimmunity in early atherosclerosis. Circulation. 2004;109:36–41
  22. Howard BV, Best L, Comuzzie A, Ebbesson SOE, Epstein SE, Fabsitz RR, et al. C-reactive protein, insulin resistance, and metabolic syndrome in a population with a high burden of subclinical infection: insights from the GOCADAN study. Diabetes Care 2008;31:2312–14.
  23. Cutchins A, Roman MJ, Devereux RB, Ebbesson SO, Umans JG, Zhu J, et al. Prevalence and correlates of subclinical atherosclerosis in Alaska Eskimos. The GOCADAN Study. Stroke. 2008;39:3079–3082
  24. Wang W, Lee E, Howard BV, et al. Statistical analysis for data collected from a family study with large and inter-related families: the Strong Heart Study, in press.
  25. Ebbesson SO, Risica PM, Ebbesson LO, Kennish JM. Eskimos have CHD despite high consumption of omega-3 fatty acids: the Alaska Siberia project. Int J Circumpolar Health. 2005;64:387–395
  26. Kjaergaard JJ, Bjerregaard P. Incidence of myocardial and cerebral infarction in Nuuk, Greenland. Int J Circumpolar Health. 2004;63(Suppl. 2):290–291
  27. Trimble B, Wainwright K, Lanier AP. Stroke in Yup'ik Eskimos. In: Presented at the American Academy of Neurology. Toronto, Canada: Scientific Session on Neuroepidemiology of Stroke; April 1999;
  28. Howard BV, Lee ET, Fabsitz RR, Robbins DC, Yeh JL, Cowan LD, et al. Diabetes and coronary heart disease in American Indians: the Strong Heart Study. Diabetes. 1996;45(Suppl. 3):S6–S13
  29. Howard BV, Lee ET, Cowan LD, Fabsitz RR, Howard WJ, Oopik AJ, et al. Coronary heart disease prevalence and its relation to risk factors in American Indians. The Strong Heart Study. Am J Epidemiol. 1995, 1;142:254–268
  30. Chambless LE, Folsom AR, Sharrett AR, Sorlie P, Couper D, Szklo M, et al. Coronary heart disease risk prediction in the Atherosclerosis Risk in Communities (ARIC) study. J Clin Epidemiol. 2003;56:880–890
  31. Rosamond W, Flegal K, Friday G, Furie K, Go A, Greenlund K, et al. Heart disease and stroke statistics – 2007 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation. 2007;115:e69–e171
  32. Carter EA, MacCluer JW, Dyke B, Howard BV, Devereux RB, Ebbesson SO, et al. Diabetes mellitus and impaired fasting glucose in Alaska Eskimos: the Genetics of Coronary Artery Disease in Alaska Natives (GOCADAN) study. Diabetologia. 2006;49:29–35
  33. Fabsitz RR, Best L, Devereux RB, et al. Hypertension prevalence, awareness, treatment and control among American Indians and Alaskan Eskimos: results from the Strong Heart and GOCADAN studies, in press.
  34. Kaufman DJ, Roman MJ, Devereux RB, Fabsitz RR, Maccluer JW, Dyke B, et al. Prevalence of smoking and its relationship with carotid atherosclerosis in Alaskan Eskimos of the Norton Sound region: The GOCADAN Study. Nicotine Tob Res. 2008;10:483–491
  35. Zhao G, Ford ES, Li C, Mokdad AH. Are United States adults with coronary heart disease meeting physical activity recommendations?. Am J Cardiol. 2008;101:557–561
  36. Thompson PD, Buchner D, Pina IL, Balady GJ, Williams MA, Marcus BH, et al. Exercise and physical activity in the prevention and treatment of atherosclerotic cardiovascular disease: a statement from the Council on Clinical Cardiology (Subcommittee on Exercise, Rehabilitation, and Prevention) and the Council on Nutrition, Physical Activity, and Metabolism (Subcommittee on Physical Activity). Circulation. 2003;107:3109–3116
  37. Smith SC, Allen J, Blair SN, Bonow RO, Brass LM, Fonarow GC, et al. AHA/ACC guidelines for secondary prevention for patients with coronary and other atherosclerotic vascular disease: 2006 update: endorsed by the National Heart, Lung, and Blood Institute. Circulation. 2006;113:2363–2372
  38. Pate RR, Pratt M, Blair SN, Haskell WL, Macera CA, Bouchard C, et al. Physical activity and public health: a recommendation from the Centers for Disease Control and Prevention and the American College of Sports Medicine. JAMA. 1995;273:402–407
  39. United States Department of Health and Human Services . Physical Activity and health: a report of the surgeon general. Atlanta, Georgia: United States Department of Health and Human Services; 1996;
  40. Ebbesson SO, Roman MJ, Devereux RB, Kaufman D, Fabsitz RR, Maccluer JW, et al. Consumption of omega-3 fatty acids is not associated with a reduction in carotid atherosclerosis: The Genetics of Coronary Artery Disease in Alaska Natives study. Atherosclerosis. 2008;199:346–353

 This study was funded by grants RO1-HL64244, U01 HL082458, and M10RR0047-34 (GCRC) from the National Heart, Lung, and Blood Institute, Bethesda, MD.

PII: S0939-4753(09)00102-1

doi: 10.1016/j.numecd.2009.04.010

Nutrition, Metabolism & Cardiovascular Diseases
Volume 20, Issue 5 , Pages 350-358 , June 2010