Nutrition, Metabolism & Cardiovascular Diseases
Volume 20, Issue 3 , Pages e9-e10 , March 2010

The high-molecular weight (HMW) form of adiponectin is a significant surrogate marker for the prediction of type 2 diabetes mellitus in the Japanese population

  • Hiroki Satoh, MD, PhD

      Affiliations

    • Corresponding Author InformationCorresponding author. Tel.: +81 11 716 1161; fax: +81 11 706 7874.

Received 5 April 2009

References 

  1. Duncan BB, Schmidt MI, Pankow JS, Bang H, Couper D, Ballantyne CM, et al. Adiponectin and the development of type 2 diabetes: the atherosclerosis risk in communities study. Diabetes. 2004;53:2473–2478
  2. Lindsay RS, Funahashi T, Hanson RL, Matsuzawa Y, Tanaka S, Tataranni PA, et al. Adiponectin and development of type 2 diabetes in the Pima Indian population. Lancet. 2002;360:57–58
  3. Snehalatha C, Mukesh B, Simon M, Viswanathan V, Haffner SM, Ramachandran A. Plasma adiponectin is an independent predictor of type 2 diabetes in Asian indians. Diabetes Care. 2003;26:3226–3229
  4. Pajvani UB, Hawkins M, Combs TP, Rajala MW, Doebber T, Berger JP, et al. Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione-mediated improvement in insulin sensitivity. J Biol Chem. 2004;279:12152–12162
  5. Waki H, Yamauchi T, Kamon J, Ito Y, Uchida S, Kita S, et al. Impaired multimerization of human adiponectin mutants associated with diabetes. Molecular structure and multimer formation of adiponectin. J Biol Chem. 2003;278:40352–40363
  6. Rizza S, Clementi F, Porzio O, Cardellini M, Savo A, Serino M, et al. Adiponectin isoforms are not associated with the severity of coronary atherosclerosis but with undiagnosed diabetes in patients affected by stable CAD. Nutr Metab Cardiovasc Dis. 2009;19:54–60
  7. Report of the Expert Committee on the diagnosis and classification of Diabetes Mellitus. Diabetes Care. 1997;20:1183–1197

PII: S0939-4753(09)00132-X

doi: 10.1016/j.numecd.2009.05.009

Nutrition, Metabolism & Cardiovascular Diseases
Volume 20, Issue 3 , Pages e9-e10 , March 2010