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Nutrition, Metabolism & Cardiovascular Diseases
Volume 21, Issue 9
, Pages 672-678
, September 2011
Olmesartan, a novel angiotensin II type 1 receptor antagonist, reduces severity of atherosclerosis in apolipoprotein E deficient mice associated with reducing superoxide production
References
- . Atherosclerosis: an inflammatory disease. N Engl J Med. 1999;340:115–126
- . Angiotensin II type 1 receptor blockers. Circulation. 2001;103:904–912
- Effects of angiotensin II infusion on the expression and function of NAD(P)H oxidase and components of nitric oxide/cGMP signaling. Circ Res. 2002;90:e58–e65
- Increased NADH-oxidase-mediated superoxide production in the early stages of atherosclerosis. Evidence for involvement of the renin-angiotensin system. Circulation. 1999;99:2027–2033
- Olmesartan, a novel AT1 antagonist, suppresses cytotoxic myocardial injury in autoimmune heart failure. Am J Physiol Heart Circ Physiol. 2005;289:H 1147–H 1152
- . Angiotensin II is chemotactic, for a T-cell subset which can express migration factor activity in murine Schistosomiasis mansoni. Cell Immunol. 1987;107:180–187
- Angiotensin II type 1 receptor blocker telmisartan suppresses superoxide production and reduces atherosclerotic lesion formation in apolipoprotein E-deficient mice. Atherosclerosis. 2006;186:402–410
- . Olmesartan and pravastatin additively reduce development of atherosclerosis in APOE*3 Leiden transgenic mice. J Hypertens. 2007;25:2454–2462
- Angiotensin receptor-1 blocker inhibits atherosclerotic changes and endothelial disruption of the aortic valve in hypercholesterolemic rabbits. J Am Coll Cardiol. 2007;49:1482–1489
- Blockade of Angiotensin II type-1 receptor reduces oxidative stress in adipose tissue and ameliorates adipocytokine dysregulation. Kidney Int. 2006;70:1717–1724
- . The regressive effect of an angiotensin II receptor blocker on formed fatty streaks in monkeys fed a high-cholesterol diet. J Hypertens. 2005;23:1879–1886
- Effect of combination of calcium antagonist, azelnidipine, and AT1 receptor blocker, olmesartan, on atherosclerosis in apolipoprotein E-deficient mice. J Hypertens. 2005;23:1383–1389
- . Use of angiotensin II receptor blockers in animal models of atherosclerosis. Am J Hypertens. 2002;15:9S–13S
- Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells. Cell. 1992;71:343–353
- . ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree. Arterioscler Thromb. 1994;14:133–140
- Severity of hyperlipidemia does not affect antiatherosclerotic effect of an angiotensin II receptor antagonist apolipoprotein E-deficient mice. J Cardiovasc Pharmacol. 2006;47:764–769
- Intraperitoneal administration of anti-c-fms monoclonal antibody prevents initial events of atherogenesis but does not reduce the size of advanced lesions in apolipoprotein E-deficient mice. Circulation. 1999;99:1740–1746
- . Effects of MCI-186 (Edaravone), a novel free radical scavenger, upon experimental atherosclerosis in apolipoprotein E-deficient mice. Circ J. 2006;70:1216–1219
- Pharmacology of CS-866, a novel nonpeptide angiotensin II receptor antagonist. Eur J Pharmacol. 1995;285:181–188
- . Superoxide production in vascular smooth muscle contributes to oxidative stress and impaired relaxation in atherosclerosis. Circ Res. 1998;82:1298–1305
- N-acetylcysteine reduces the severity of atherosclerosis in apolipoprotein E deficient mice via reducing superoxide production. Circ J. 2008;73:1337–1341
- Overexpression of thioredoxin-1 in transgenic mice attenuates adriamycin-induced cardiotoxicity. Circulation. 2002;106:1403–1409
- Difference in thioredoxin expression in viral myocarditis in inbred strains of mice. Jpn Circ J. 2001;65:561–564
- . Serum thioredoxin (TRX) levels in patients with heart failure. Jpn Circ J. 2001;65:491–494
- . Role of MIP-2 in coxsackie virus B3 myocarditis. J Mol Cell Cardiol. 2000;32:631–638
- . Association of inflammatory marker and highly sensitive C-reactive protein with aerobic exercise capacity, maximum oxygen uptake and insulin resistance in healthy middle-aged volunteers. Circ J. 2005;69:452–457
- Anti-inflammatory effects of exercise training in the skeletal muscle of patients with chronic heart failure. J Am Coll Cardiol. 2003;42:869–872
- . Reduction in C-reactive protein through cardiac rehabilitation and exercise training. J Am Coll Cardiol. 2004;43:1056–1061
- . Immunoglobulin treatment suppresses atherosclerosis in apolipoprotein E-deficient mice via the Fc portion. Am J Physiol. 2003;285:H899–H906
- . Fc receptor-mediated inhibitory effect of immunoglobulin therapy on autoimmune giant cell myocarditis: concomitant suppression of the expression of dendritic cells. Circ Res. 2001;89:540–546
- . Immunoglobulin treatment reduces atherosclerosis in apo E knockout mice. J Clin Invest. 1998;102:910–918
- . Oxidants and antioxidants in atherogenesis: an appraisal. J Lipid Res. 1999;40:2143–2157
- Vascular respiratory uncoupling increases blood pressure and atherosclerosis. Nature. 2005;435:502–506
- Physical activity, plasma antioxidant capacity, and endothelium-dependent vasodilation in young and older men. Am J Hypertens. 2005;18:510–516
- Angiotensin II-induced superoxide anion generation in human vascular endothelial cells: role of membrane-bound NADH/NADPH-oxidases. Cardiovasc Res. 1999;44:215–222
- Superoxide production and expression of nox family proteins in human atherosclerosis. Circulation. 2002;105:1429–1435
- . Regulation of superoxide anion production by NADPH oxidase in monocytes/macrophages: contributions to atherosclerosis. Arterioscler Thromb Vasc Biol. 2004;24:23–28
- . Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro. Implications for atherosclerotic plaque stability. J Clin Invest. 1996;98:2572–2579
- Inhibitory effects of AT1 receptor blocker, olmesartan, and estrogen on atherosclerosis via anti-oxidative stress. Hypertension. 2005;45:545–551
- Monocyte chemoattractant protein-1 is an essential inflammatory mediator in angiotensin II-induced progression of established atherosclerosis in hypercholesterolemic mice. Arterioscler Thromb Vasc Biol. 2004;24:534–539
☆ Supported in part by research grants from The Univers Foundation, Chiyoda Kenko Organization, The Nakatomi Foundation, and Japanese Ministry of Education, Science, and Culture (18596772).
PII: S0939-4753(10)00015-3
doi: 10.1016/j.numecd.2009.12.016
© 2010 Elsevier B.V. All rights reserved.
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Nutrition, Metabolism & Cardiovascular Diseases
Volume 21, Issue 9
, Pages 672-678
, September 2011
