Nutrition, Metabolism & Cardiovascular Diseases
Volume 21, Issue 9 , Pages 628-635 , September 2011

Effect of the Mediterranean diet with and without weight loss on cardiovascular risk factors in men with the metabolic syndrome

  • C. Richard

      Affiliations

    • Institute of Nutraceuticals and Functional Foods, Laval University, 2440, boul. Hochelaga, Québec (Qc), Canada G1V 0A6
  • ,
  • P. Couture

      Affiliations

    • Institute of Nutraceuticals and Functional Foods, Laval University, 2440, boul. Hochelaga, Québec (Qc), Canada G1V 0A6
    • Lipid Research Center, CHUQ Research Center, Quebec, Canada
  • ,
  • S. Desroches

      Affiliations

    • Institute of Nutraceuticals and Functional Foods, Laval University, 2440, boul. Hochelaga, Québec (Qc), Canada G1V 0A6
  • ,
  • A. Charest

      Affiliations

    • Institute of Nutraceuticals and Functional Foods, Laval University, 2440, boul. Hochelaga, Québec (Qc), Canada G1V 0A6
  • ,
  • B. Lamarche

      Affiliations

    • Institute of Nutraceuticals and Functional Foods, Laval University, 2440, boul. Hochelaga, Québec (Qc), Canada G1V 0A6
    • Corresponding Author InformationCorresponding author. Tel.: +1 418 656 2131x4355; fax: +1 418 656 5877.

Received 2 October 2009 ,Revised 18 January 2010 ,Accepted 20 January 2010.

References 

  1. Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, Franklin BA, et al. Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation. 2005;112:2735–2752
  2. Ford ES, Giles WH, Dietz WH. Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey. JAMA. 2002;287:356–359
  3. Galassi A, Reynolds K, He J. Metabolic syndrome and risk of cardiovascular disease: a meta-analysis. Am J Med. 2006;119:812–819
  4. Case CC, Jones PH, Nelson K, O'Brian Smith E, Ballantyne CM. Impact of weight loss on the metabolic syndrome. Diabetes Obes Metab. 2002;4:407–414
  5. Lofgren IE, Herron KL, West KL, Zern TL, Brownbill RA, Ilich JZ, et al. Weight loss favorably modifies anthropometrics and reverses the metabolic syndrome in premenopausal women. J Am Coll Nutr. 2005;24:486–493
  6. Meydani M. A Mediterranean-style diet and metabolic syndrome. Nutr Rev. 2005;63:312–314
  7. Panagiotakos DB, Polychronopoulos E. The role of Mediterranean diet in the epidemiology of metabolic syndrome: converting epidemiology to clinical practice. Lipids Health Dis. 2005;4:7
  8. Gray-Donald K, Jacobs-Starkey L, Johnson-Down L. Food habits of Canadians: reduction in fat intake over a generation. Can J Public Health. 2000;91:381–385
  9. The Mediterranean diet: constituents and health promotion. Boca Raton, FL: CRC Press; 2001;
  10. Couillard C, Despres JP, Lamarche B, Bergeron J, Gagnon J, Leon AS, et al. Effects of endurance exercise training on plasma HDL cholesterol levels depend on levels of triglycerides: evidence from men of the Health, Risk Factors, Exercise Training and Genetics (HERITAGE) family study. Arterioscler Thromb Vasc Biol. 2001;21:1226–1232
  11. Richterich R, Dauwalder H. Determination of plasma glucose by hexokinase-glucose-6-phosphate dehydrogenase method, Schweiz Med Wochenschr. 1971;101:615–618
  12. Desbuquois B, Aurbach GD. Use of polyethylene glycol to separate free and antibody-bound peptide hormones in radioimmunoassays. J Clin Endocrinol Metab. 1971;33:732–738
  13. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28:412–419
  14. Lohman T, Roche AF, Martorell R. The Airlie (VA) consensus conference. Anthropometric standardization reference manual. Champaign, IL: Human Kinetics; 1988;pp. 39–80
  15. Alvarez Leon EE, Henriquez P, Serra-Majem L. Mediterranean diet and metabolic syndrome: a cross-sectional study in the Canary Islands. Public Health Nutr. 2006;9:1089–1098
  16. Estruch R, Martinez-Gonzalez MA, Corella D, Salas-Salvado J, Ruiz-Gutierrez V, Covas MI, et al. Effects of a Mediterranean-style diet on cardiovascular risk factors: a randomized trial. Ann Intern Med. 2006;145:1–11
  17. Panagiotakos DB, Pitsavos C, Chrysohoou C, Skoumas J, Tousoulis D, Toutouza M, et al. Impact of lifestyle habits on the prevalence of the metabolic syndrome among Greek adults from the ATTICA study. Am Heart J. 2004;147:106–112
  18. Salas-Salvado J, Fernandez-Ballart J, Ros E, Martinez-Gonzalez MA, Fito M, Estruch R, et al. Effect of a Mediterranean diet supplemented with nuts on metabolic syndrome status: one-year results of the PREDIMED randomized trial. Arch Intern Med. 2008;168:2449–2458
  19. Tortosa A, Bes-Rastrollo M, Sanchez-Villegas A, Basterra-Gortari FJ, Nunez-Cordoba JM, Martinez-Gonzalez MA. Mediterranean diet inversely associated with the incidence of metabolic syndrome: the SUN prospective cohort. Diabetes Care. 2007;30:2957–2959
  20. Jula A, Marniemi J, Huupponen R, Virtanen A, Rastas M, Ronnemaa T. Effects of diet and simvastatin on serum lipids, insulin, and antioxidants in hypercholesterolemic men: a randomized controlled trial. JAMA. 2002;287:598–605
  21. Babio N, Bullo M, Basora J, Martinez-Gonzalez MA, Fernandez-Ballart J, Marquez-Sandoval F, et al. Adherence to the Mediterranean diet and risk of metabolic syndrome and its components. Nutr Metab Cardiovasc Dis. 2009;
  22. Esposito K, Marfella R, Ciotola M, Di Palo C, Giugliano F, Giugliano G, et al. Effect of a Mediterranean-style diet on endothelial dysfunction and markers of vascular inflammation in the metabolic syndrome: a randomized trial. JAMA. 2004;292:1440–1446
  23. Dattilo AM, Kris-Etherton PM. Effects of weight reduction on blood lipids and lipoproteins: a meta-analysis. Am J Clin Nutr. 1992;56:320–328
  24. Shai I, Schwarzfuchs D, Henkin Y, Shahar DR, Witkow S, Greenberg I, et al. Weight loss with a low-carbohydrate, Mediterranean, or low-fat diet. N Engl J Med. 2008;359:229–241

PII: S0939-4753(10)00032-3

doi: 10.1016/j.numecd.2010.01.012

Nutrition, Metabolism & Cardiovascular Diseases
Volume 21, Issue 9 , Pages 628-635 , September 2011