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A gene variation (rs12691) in the CCAT/enhancer binding protein α modulates glucose metabolism in metabolic syndrome
24 January 2012
J. Delgado-Lista, P. Perez-Martinez, A. Garcia-Rios, C.M. Phillips, W. Hall, I.M.F. Gjelstad, D. Lairon, W. Saris, B. Kieć-Wilk, B. Karlström, C.A. Drevon, C. Defoort, E.E. Blaak, A. Dembinska-Kieć, U. Risérus, J.A. Lovegrove, H.M. Roche, J. Lopez-Miranda
Abstract: Background and aims: CCAAT/enhancer-binding protein alpha (CEBPA) is a transcription factor involved in adipogenesis and energy homeostasis. Caloric restriction reduces CEBPA protein express...
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Can vitamin D deficiency cause diabetes and cardiovascular diseases? Present evidence and future perspectives
24 January 2012
G. Muscogiuri, G.P. Sorice, R. Ajjan, T. Mezza, S. Pilz, A. Prioletta, R. Scragg, S.L. Volpe, M.D. Witham, A. Giaccari
Abstract: Several studies have shown that vitamin D may play a role in many biochemical mechanisms in addition to bone and calcium metabolism. Recently, vitamin D has sparked widespread interest becau...
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Lower plasma NAMPT/visfatin levels are associated with impaired hepatic mitochondrial function in non-diabetic obese women: A potential link between obesity and non-alcoholic fatty liver disease
09 January 2012
J.R. Ruiz, A. Lasa, E. Simon, E. Larrarte, I. Labayen
Non-alcoholic fatty liver disease (NAFLD) is strongly associated with type 2 diabetes. Hepatic mitochondrial dysfunction precedes the development of NAFLD, insulin resistance and inflammation . The 2-...
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Homocysteinylation of low-density lipoproteins (LDL) from subjects with type 1 diabetes and human aortic endothelial cells: An in vitro study
04 January 2012
L. Nanetti, F. Raffaelli, G. Ferretti, T. Bacchetti, R.A. Rabini, L. Mazzanti, A. Vignini
Type 1 (T1D) and Type 2 (T2D) diabetes are independent risk factors for cardiovascular disease (CVD), stroke and coronary artery disease . The higher risk of CVD associated with diabetes has been rela...
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What is common becomes normal: The effect of obesity prevalence on maternal perception
04 January 2012
N. Binkin, A. Spinelli, G. Baglio, A. Lamberti
Abstract: Background and aims: This analysis investigates the poorly-known effect of local prevalence of childhood obesity on mothers’ perception of their children’s weight status. Methods and results...
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