Abstract
Background and aims
It was reported that high coffee consumption was related to decreased diabetes risk.
The aim of this study is to examine the association between coffee consumption and
the incidence of type 2 diabetes in persons with normal glucose tolerance in a population
with a high incidence and prevalence of diabetes.
Methods and results
In a prospective cohort study, information about daily coffee consumption was collected
at the baseline examination (1989–1992) in a population-based sample of American Indian
men and women 45–74 years of age. Participants with normal glucose tolerance (N = 1141) at the baseline examination were followed for an average of 7.6 years. The
incidence of diabetes was compared across the categories of daily coffee consumption.
The hazard ratios of diabetes related to coffee consumption were calculated using
Cox proportional hazards models, adjusted for potential confounders.
Levels of coffee consumption were positively related to levels of current smoking
and inversely related to body mass index, waist circumference, female gender, and
hypertension. Compared to those who did not drink coffee, participants who drank 12
or more cups of coffee daily had 67% less risk of developing diabetes during the follow-up
(hazard ratio: 0.33, 95% confidence interval: 0.13, 0.81).
Conclusion
In this population, a high level of coffee consumption was associated with a reduced
risk of deterioration of glucose metabolism over an average 7.6 years of follow-up.
More work is needed to understand whether there is a plausible biological mechanism
for this observation.
Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Nutrition, Metabolism and Cardiovascular DiseasesAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
CDC: National diabetes fact sheet; 2007. In.
- Coffee consumption and risk of type 2 diabetes, cardiovascular diseases, and cancer.Appl Physiol Nutr Metab. 2008; 33: 1269-1283
- Coffee consumption and risk of coronary heart disease: a meta-analysis.Nutr Metab Cardiovasc Dis. 2007; 17: 209-223
- Coffee consumption and risk of type 2 diabetes mellitus among middle-aged Finnish men and women.JAMA. 2004; 291: 1213-1219
- Coffee consumption and risk for type 2 diabetes mellitus.Ann Intern Med. 2004; 140: 1-8
- Coffee consumption and risk of type 2 diabetes mellitus.Lancet. 2002; 360: 1477-1478
- Coffee and incidence of diabetes in Swedish women: a prospective 18-year follow-up study.J Intern Med. 2004; 255: 89-95
- Coffee, caffeine, and risk of type 2 diabetes: a prospective cohort study in younger and middle-aged U.S. women.Diabetes Care. 2006; 29: 398-403
- Coffee consumption and risk of type 2 diabetes in finnish twins.Int J Epidemiol. 2004; 33: 616-617
- Does coffee consumption reduce the risk of type 2 diabetes in individuals with impaired glucose?.Diabetes Care. 2006; 29: 2385-2390
- Coffee consumption and risk of type 2 diabetes mellitus: an 11-year prospective study of 28 812 postmenopausal women.Arch Intern Med. 2006; 166: 1311-1316
- Coffee and sweetened beverage consumption and the risk of type 2 diabetes mellitus: the atherosclerosis risk in communities study.Am J Epidemiol. 2006; 164: 1075-1084
- Coffee consumption and risk of type 2 diabetes: a systematic review.JAMA. 2005; 294: 97-104
- Incidence of diabetes in American Indians of three geographic areas: the strong heart study.Diabetes Care. 2002; 25: 49-54
- Diabetes and impaired glucose tolerance in three American Indian populations aged 45-74 years. The strong heart study.Diabetes Care. 1995; 18: 599-610
- The strong heart study. A study of cardiovascular disease in American Indians: design and methods.Am J Epidemiol. 1990; 132: 1141-1155
- Risk factors for coronary heart disease in diabetic and nondiabetic Native Americans. The strong heart study.Diabetes. 1992; 41: 4-11
- Parity, postmenopausal estrogen use, and cardiovascular disease risk factors in American Indian women: the strong heart study.J Women's Health. 1997; 6: 441-449
- Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation.Diabetic Med. 1998; 15 ([see comment]): 539-553
- The assessment of historical physical activity and its relation to adult bone parameters.Am J Epidemiol. 1988; 127: 1053-1063
- Parity, postmenopausal estrogen use, and cardiovascular disease risk factors in American Indian women: the Strong Heart Study.J Womens Health. 1997; 6: 441-449
- Hypertension in adult American Indians. The strong heart study.Hypertension. 1996; 28: 256-264
- Coffee consumption and the incidence of type 2 diabetes.Diabetes Care. 2003; 26: 2211-2212
- Coffee and type 2 diabetes: from beans to beta-cells.Nutr Metab Cardiovasc Dis. 2006; 16: 69-77
- Intakes of antioxidants in coffee, wine, and vegetables are correlated with plasma carotenoids in humans.J Nutr. 2004; 134: 562-567
- Contribution of beverages to the intake of lipophilic and hydrophilic antioxidants in the Spanish diet.Eur J Clin Nutr. 2003; 57: 1275-1282
- Is oxidative stress the pathogenic mechanism underlying insulin resistance, diabetes, and cardiovascular disease? The common soil hypothesis revisited.Arterioscler Thromb Vasc Biol. 2004; 24: 816-823
- Chlorogenic acids and other cinnamates - nature, occurrence, dietary burden, absorption and metabolism.J Sci Food Agric. 2000; 80: 1033-1043
- Coffee acutely modifies gastrointestinal hormone secretion and glucose tolerance in humans: glycemic effects of chlorogenic acid and caffeine.Am J Clin Nutr. 2003; 78: 728-733
- Chlorogenic acid and hydroxynitrobenzaldehyde: new inhibitors of hepatic glucose 6-phosphatase.Arch Biochem Biophys. 1997; 339: 315-322
- Thermogenic, metabolic, and cardiovascular responses to ephedrine and caffeine in man.Int J Obes Relat Metab Disord. 1993; 17: S41-S43
- Caffeine ingestion and muscle metabolism during prolonged exercise in humans.Am J Physiol. 1992; 262: E891-E898
- Coffee, tea and diabetes: the role of weight loss and caffeine.Int J Obes. 2005; 29: 1121-1129
- Caffeine can decrease insulin sensitivity in humans.Diabetes Care. 2002; 25: 364-369
- Tolerance to the humoral and hemodynamic effects of caffeine in man.J Clin Invest. 1981; 67: 1111-1117
- Coffee consumption and risk of type 2 diabetes mellitus.Lancet. 2003; 361: 703
- Dietary fiber, glycemic load, and risk of non-insulin-dependent diabetes mellitus in women.JAMA. 1997; 277: 472-477
- Carbohydrates, dietary fiber, and incident type 2 diabetes in older women.Am J Clin Nutr. 2000; 71: 921-930
- Critical review of dietary caffeine and blood pressure: a relationship that should be taken more seriously.Psychosom Med. 2004; 66: 63-71
- Systematic review on the effectiveness of caffeine abstinence on the quality of sleep.J Clin Nurs. 2009; 18: 13-21
Article info
Publication history
Published online: February 19, 2010
Accepted:
October 30,
2009
Received in revised form:
October 15,
2009
Received:
January 21,
2009
Footnotes
☆The opinions expressed in this paper are those of the authors and do not necessarily reflect the views of the Indian Health Service.
Identification
Copyright
© 2009 Elsevier B.V. Published by Elsevier Inc. All rights reserved.
